Early Embryo Development
Over the last 12 years, my research group and I have been performing and analyzing time-lapse videos of early mouse development - beginning at the one-cell (also known as "zygote") stage and continuing to the blastocyst stage.
The team has also been performing RNA inhibition experiments (a technology that produces "gene knock-out") to better understand the controlling mechanisms of early mouse embryo development. Two U.S. Scientists were honored with the Nobel Prize in 2006 for their novel RNA inhibition work.
In 2008, my colleague, Dr. Kristin Gunsalus, and I were awarded $1 million dollars from the NIH to continue these studies.
Our group has also received honorable mention two years in a row from the American Society of Reproductive Medicine (ASRM) for technical achievement of submitted embryology videos.