Dr. Nicole Noyes

Reproductive Endocrinologist
Specializing in Infertility,
In Vitro Fertilization (IVF),
Egg Freezing and Embryo Banking

Recent Publications


I am a fellow of the American College of Obstetricians and Gynecologists (FACOG) and an active member in the American Society for Reproductive Medicine (ASRM) and the American Society of Clinical Oncology. I am past Chair of the ASRM's Special Interest Group - Fertility Preservation, the largest interest group of the society. I am also active in the European Society of Human Reproduction and Embryology (ESHRE).


I have published over 120 abstracts and articles in peer review journals and given over 85 lectures related to infertility and fertility preservation. The following is a partial list of my most recent work. Another way to view my publications is to google me or search my name online at PubMed: https://www.ncbi.nlm.nih.gov/pubmed/

Latest Top (15) News

The evolving landscape of donor egg treatment: success, women's choice, and anonymity
CONCLUSION: The use of FRESH-EGG with FRESH-ET without PGT-A remains superior to newer DE treatment combinations. Specifically, the use of FROZEN-EGG and PGT-A did not improve outcomes. Although changing DE practices may enhance experience and affordability, patients and providers must appreciate that choices do not always favorably impact success. Additionally, newly available genetic-ancestry testing may pose longer-term ramifications mandating change in treatment and/or counseling.

Sun, 20 Jun 2021 06:00:00 -0400

Effect of subclinical mastitis detected in the first month of lactation on somatic cell count linear scores, milk yield, fertility, and culling of dairy cows in certified organic herds
It is well established that subclinical mastitis (SCM), characterized by somatic cell count (SCC) >200,000 cells/mL, has a negative effect on the productivity, reproductive performance, and survivability of cows from conventional dairy herds. However, in organic herds, where the use of antimicrobial drugs is restricted for the treatment and control of intramammary infections (IMI) in dairy cows, little is known about the effect of SCM on performance and survivability. The objective of this study...

Mon, 14 Dec 2020 06:00:00 -0500

Young Women’s Attitudes Towards Modern Reproductive Practices: A Survey Study Assessing What Young Women Want
CONCLUSION: Reproductive autonomy and fertility preservation are important to young educated females, a population sought-after for oocyte donation. Potential donors’ desires for additional rights merit consideration as oocyte demand increases and frozen-oocyte banks emerge.

Thu, 20 Sep 2018 06:00:00 -0400

Pregnancy Outcomes After Fertility Preservation in Transgender Men
CONCLUSION: Transgender men with cryopreserved gametes can build families in a way that affirms their gender identity. Obstetrician-gynecologists should be familiar with the fertility needs of transgender patients so appropriate discussions and referrals can be made.

Wed, 10 May 2017 06:00:00 -0400

Successful Oocyte Cryopreservation in Reproductive-Aged Cancer Survivors
CONCLUSION: Oocyte cryopreservation is now a feasible fertility preservation option for reproductive-aged patients with cancer who require gonadotoxic therapies.

Tue, 09 Feb 2016 06:00:00 -0500

Baby budgeting: oocyte cryopreservation in women delaying reproduction can reduce cost per live birth
CONCLUSION(S): In women who plan to delay childbearing until age 40 years, oocyte cryopreservation before 38 years of age reduces the cost to obtain a live birth.

Sat, 28 Mar 2015 06:00:00 -0400

Long-term cryopreservation of human oocytes does not increase embryonic aneuploidy
CONCLUSION(S): Embryos derived from cryopreserved oocytes demonstrate impaired blastulation but equivalent rates of euploidy, implantation, and live birth compared with blastocysts derived from fresh oocytes, supporting the safety and efficacy of oocyte cryopreservation.

Sun, 28 Dec 2014 06:00:00 -0500

What makes them split? Identifying risk factors that lead to monozygotic twins after in vitro fertilization
CONCLUSION(S): After IVF the incidence of MZT is high, with young oocyte age, year of treatment, and extended culture (or embryo stage at transfer) conferring greatest risk. Regarding MZT type, assisted reproductive technology (ART) procedures may influence the timing of embryonic splitting (i.e., division in early embryonic development may be influenced by zona pellucida [ZP] manipulation whereas later splitting may occur during delayed implantation). Poor obstetric/perinatal outcome is...

Tue, 06 May 2014 06:00:00 -0400

Live birth in a 46 year old using autologous oocytes cryopreserved for a duration of 3 years: a case report documenting fertility preservation at an advanced reproductive age
No abstract

Tue, 11 Mar 2014 06:00:00 -0400

What do reproductive-age women who undergo oocyte cryopreservation think about the process as a means to preserve fertility?
CONCLUSION(S): Surveying oocyte cryopreservation patients provides a glimpse into the knowledge base and motivations surrounding current female reproductive practices. Oocyte cryopreservation technology may prove to bridge the gap between reproductive prime and when a woman is realistically "ready" to have children.

Tue, 20 Aug 2013 06:00:00 -0400

Experiences in fertility preservation: lessons learned to ensure that fertility and reproductive autonomy remain options for cancer survivors
CONCLUSIONS: Our data demonstrate that oocyte and/or zygote banking are feasible FP options for women with malignancy; given the choice, the majority elected oocyte cryopreservation, highlighting desire for reproductive autonomy. Continued growth and research, combined with interdisciplinary communication, will ensure that appropriate candidates are offered FP and the potential for future parenthood, an important quality-of-life marker for survivors.

Thu, 15 Aug 2013 06:00:00 -0400

Oocyte efficiency: does live birth rate differ when analyzing cryopreserved and fresh oocytes on a per-oocyte basis?
CONCLUSION(S): Our data suggest that while assisted reproductive technology remains an inefficient process, OC may be approaching fresh IVF when live birth is the primary consideration. However, OC may negatively impact the potential for blastocyst formation.

Sat, 01 Jun 2013 06:00:00 -0400

Oocyte cryopreservation as a fertility preservation measure for cancer patients
Advances in cancer treatment have allowed women to live longer, fuller lives. However, gonadotoxic therapies used to effect cancer 'cures' often significantly impair a woman's reproductive potential. Thus, in accordance with improved survival rates,there is an increase in demand for fertility preservation. Initially, fertility preservation was limited to embryo cryopreservation;therefore, the number of patients enrolling was relatively low. Recently, substantial improvements have increased...

Tue, 17 May 2011 06:00:00 -0400

Retrospective analysis of outcomes following transfer of previously cryopreserved oocytes, pronuclear zygotes and supernumerary blastocysts
Oocyte cryopreservation still bears the experimental label. Remarkable innovation in this field has led to immense improvement in clinical outcomes and has even resulted in outcomes comparable to those achieved following fresh embryo transfers. Such success has prompted this centre to investigate outcomes of cryopreservation options (oocyte versus pronuclear zygote versus supernumerary day-5 blastocyst after fresh embryo transfer). This study retrospectively analysed 200 cryopreservation cycles...

Tue, 10 May 2011 06:00:00 -0400

Treatment outcomes and quality-of-life assessment in a university-based fertility preservation program: results of a registry of female cancer patients at 2 years
CONCLUSIONS: Fertility preservation remains a significant issue for cancer patients. With early reproductive endocrinologist referral, cancer treatment delay is minimized and FP outcomes are optimized.

Wed, 23 Mar 2011 06:00:00 -0400