Nicole Noyes M.D.

I am a fellow of the American College of Obstetricians and Gynecologists (FACOG) and an active member in the American Society for Reproductive Medicine (ASRM) and the American Society of Clinical Oncology. I am past Chair of the ASRM’s Special Interest Group – Fertility Preservation, the largest interest group of the society. I am also active in the European Society of Human Reproduction and Embryology (ESHRE). I have published over 120 abstracts and articles in peer review journals and given over 85 lectures related to infertility and fertility preservation. The following is a partial list of my most recent work. Another way to view my publications is to google me or search my name online at PubMed:

Link to Dr. Noyes’s publications available on PubMed.

Introduction. Symposium: oocyte cryopreservation.

Nagy ZP, Noyes N.Reprod Biomed Online. 2011 Sep;23(3):279-80. doi: 10.1016/j.rbmo.2011.05.015. Epub 2011 May 27.PMID: 21764379 No abstract available.2CiteShare 

Fertility considerations in the management of gynecologic malignancies.

Noyes N, Knopman JM, Long K, Coletta JM, Abu-Rustum NR.Gynecol Oncol. 2011 Mar;120(3):326-33. doi: 10.1016/j.ygyno.2010.09.012. Epub 2010 Oct 13.PMID: 20943258 Review.3CiteShare 

Oocyte cryopreservation as a fertility preservation measure for cancer patients.

Noyes N, Knopman JM, Melzer K, Fino ME, Friedman B, Westphal LM.Reprod Biomed Online. 2011 Sep;23(3):323-33. doi: 10.1016/j.rbmo.2010.11.011. Epub 2010 Nov 24.PMID: 21570353 Review.4CiteShare 

Oocyte cryopreservation: is it time to remove its experimental label?

Noyes N, Boldt J, Nagy ZP.J Assist Reprod Genet. 2010 Feb;27(2-3):69-74. doi: 10.1007/s10815-009-9382-y. Epub 2010 Feb 6.PMID: 20140641 Free PMC article. Review.5CiteShare 

Surviving childhood and reproductive-age malignancy: effects on fertility and future parenthood.

Knopman JM, Papadopoulos EB, Grifo JA, Fino ME, Noyes N.Lancet Oncol. 2010 May;11(5):490-8. doi: 10.1016/S1470-2045(09)70317-1. Epub 2010 Feb 12.PMID: 20153978 Review.6CiteShare 

Successful Oocyte Cryopreservation in Reproductive-Aged Cancer Survivors.

Druckenmiller S, Goldman KN, Labella PA, Fino ME, Bazzocchi A, Noyes N.Obstet Gynecol. 2016 Mar;127(3):474-480. doi: 10.1097/AOG.0000000000001248.PMID: 268550927CiteShare 

Is intracytoplasmic sperm injection overused?

Hodes-Wertz B, Mullin CM, Adler A, Noyes N, Grifo JA, Berkeley AS.J Urol. 2012 Feb;187(2):602-6. doi: 10.1016/j.juro.2011.09.151. Epub 2011 Dec 15.PMID: 221771778CiteShare 

Self-reported leisure time exercise change during smoking cessation in men and women.

Harrison K, Noyes N, Friedrichsen S, Tosun N, Oyenuga A, Allen S.Addict Behav. 2019 Dec;99:106025. doi: 10.1016/j.addbeh.2019.06.014. Epub 2019 Jun 13.PMID: 31412300 Free PMC article. No abstract available.9CiteShare 

The evolving landscape of donor egg treatment: success, women’s choice, and anonymity.

Peyser A, Brownridge S, Rausch M, Noyes N.J Assist Reprod Genet. 2021 Sep;38(9):2327-2332. doi: 10.1007/s10815-021-02262-6. Epub 2021 Jun 20.PMID: 34148151 Free PMC article.10CiteShare 

Fate of cryopreserved donor embryos.

Knopman JM, Talebian S, Berkeley AS, Grifo JA, Noyes N, Licciardi F.Fertil Steril. 2010 Oct;94(5):1689-92. doi: 10.1016/j.fertnstert.2009.11.010. Epub 2010 Jan 13.PMID: 20056205 Free article.11CiteShare 

Pregnancy Outcomes After Fertility Preservation in Transgender Men.

Maxwell S, Noyes N, Keefe D, Berkeley AS, Goldman KN.Obstet Gynecol. 2017 Jun;129(6):1031-1034. doi: 10.1097/AOG.0000000000002036.PMID: 2848637212CiteShare 

Optimizing embryo selection with day 5 transfer.

Reh A, Fino E, Krey L, Berkeley A, Noyes N, Grifo J.Fertil Steril. 2010 Feb;93(2):609-15. doi: 10.1016/j.fertnstert.2009.02.070. Epub 2009 Apr 14.PMID: 19368915 Free article.13CiteShare 

Achieving the “ideal” family size at advanced reproductive ages through oocyte cryopreservation.

DeVore S, Noyes N, Grifo JA, Berkeley AS, Licciardi F, Goldman KN.J Assist Reprod Genet. 2019 Feb;36(2):277-282. doi: 10.1007/s10815-018-1303-5. Epub 2018 Sep 7.PMID: 30194616 Free PMC article. No abstract available.14CiteShare 

Long-term cryopreservation of human oocytes does not increase embryonic aneuploidy.

Goldman KN, Kramer Y, Hodes-Wertz B, Noyes N, McCaffrey C, Grifo JA.Fertil Steril. 2015 Mar;103(3):662-8. doi: 10.1016/j.fertnstert.2014.11.025. Epub 2014 Dec 24.PMID: 25542819 Free article.15CiteShare 

Clinical error rates of next generation sequencing and array comparative genomic hybridization with single thawed euploid embryo transfer.

Friedenthal J, Maxwell SM, Tiegs AW, Besser AG, McCaffrey C, Munné S, Noyes N, Grifo JA.Eur J Med Genet. 2020 May;63(5):103852. doi: 10.1016/j.ejmg.2020.103852. Epub 2020 Jan 20.PMID: 3197237116CiteShare 

Embryo biopsy: the fate of abnormal pronuclear embryos.

Noyes N, Fino ME, Krey L, McCaffrey C, Adler A, Grifo J.Reprod Biomed Online. 2008 Dec;17(6):782-8. doi: 10.1016/s1472-6483(10)60405-1.PMID: 1907996117CiteShare 

Baby budgeting: oocyte cryopreservation in women delaying reproduction can reduce cost per live birth.

Devine K, Mumford SL, Goldman KN, Hodes-Wertz B, Druckenmiller S, Propst AM, Noyes N.Fertil Steril. 2015 Jun;103(6):1446-53.e1-2. doi: 10.1016/j.fertnstert.2015.02.029. Epub 2015 Mar 23.PMID: 25813281 Free PMC article.18CiteShare 

Oocyte cryopreservation: a feasible fertility preservation option for reproductive age cancer survivors.

Noyes N, Labella PA, Grifo J, Knopman JM.J Assist Reprod Genet. 2010 Aug;27(8):495-9. doi: 10.1007/s10815-010-9434-3. Epub 2010 May 18.PMID: 20480389 Free PMC article.19CiteShare 

Monozygotic twinning: an eight-year experience at a large IVF center.

Knopman J, Krey LC, Lee J, Fino ME, Novetsky AP, Noyes N.Fertil Steril. 2010 Jul;94(2):502-10. doi: 10.1016/j.fertnstert.2009.03.064. Epub 2009 May 5.PMID: 19409556 Free article.20CiteShare 

Transabdominal ultrasound-assisted embryo transfer and pregnancy outcome.

Flisser E, Grifo JA, Krey LC, Noyes N.Fertil Steril. 2006 Feb;85(2):353-7. doi: 10.1016/j.fertnstert.2005.08.015.PMID: 16595211 Free article.21CiteShare 

WITHDRAWN: What makes them split? Identifying risk factors that lead to monozygotic twins after in vitro fertilization.

Knopman JM, Krey LC, Oh C, Lee J, McCaffrey C, Noyes N.Fertil Steril. 2013 Oct 7:S0015-0282(13)03019-7. doi: 10.1016/j.fertnstert.2013.08.053. Online ahead of print.PMID: 2411253022CiteShare 

Oocyte efficiency: does live birth rate differ when analyzing cryopreserved and fresh oocytes on a per-oocyte basis?

Goldman KN, Noyes NL, Knopman JM, McCaffrey C, Grifo JA.Fertil Steril. 2013 Sep;100(3):712-7. doi: 10.1016/j.fertnstert.2013.04.040. Epub 2013 May 28.PMID: 23721713 Free article.23CiteShare 

Are gonadotropin-releasing hormone agonists losing popularity? Current trends at a large fertility center.

Reh A, Krey L, Noyes N.Fertil Steril. 2010 Jan;93(1):101-8. doi: 10.1016/j.fertnstert.2008.09.048. Epub 2008 Oct 29.PMID: 18973891 Free article.24CiteShare 

Women with cancer undergoing ART for fertility preservation: a cohort study of their response to exogenous gonadotropins.

Knopman JM, Noyes N, Talebian S, Krey LC, Grifo JA, Licciardi F.Fertil Steril. 2009 Apr;91(4 Suppl):1476-8. doi: 10.1016/j.fertnstert.2008.07.1727. Epub 2008 Sep 18.PMID: 18804204 Free article.25CiteShare 

Oocyte cryopreservation outcomes including pre-cryopreservation and post-thaw meiotic spindle evaluation following slow cooling and vitrification of human oocytes.

Noyes N, Knopman J, Labella P, McCaffrey C, Clark-Williams M, Grifo J.Fertil Steril. 2010 Nov;94(6):2078-82. doi: 10.1016/j.fertnstert.2010.01.019. Epub 2010 Feb 26.PMID: 20188356 Free article.26CiteShare 

What makes them split? Identifying risk factors that lead to monozygotic twins after in vitro fertilization.

Knopman JM, Krey LC, Oh C, Lee J, McCaffrey C, Noyes N.Fertil Steril. 2014 Jul;102(1):82-9. doi: 10.1016/j.fertnstert.2014.03.039. Epub 2014 Apr 29.PMID: 24794318 Free article.27CiteShare 

Assessing morphokinetic parameters via time lapse microscopy (TLM) to predict euploidy: are aneuploidy risk classification models universal?

Kramer YG, Kofinas JD, Melzer K, Noyes N, McCaffrey C, Buldo-Licciardi J, McCulloh DH, Grifo JA.J Assist Reprod Genet. 2014 Sep;31(9):1231-42. doi: 10.1007/s10815-014-0285-1. Epub 2014 Jun 25.PMID: 24962789 Free PMC article.28CiteShare 

Early serum interleukin-8 evaluation may prove useful in localizing abnormally implanted human gestations after in vitro fertilization.

Morelli SS, Keegan DA, Krey LC, Katz J, Liu M, Noyes N.Fertil Steril. 2008 Dec;90(6):2068-72. doi: 10.1016/j.fertnstert.2007.10.063. Epub 2008 Feb 4.PMID: 18249366 Free article.29CiteShare 

What do reproductive-age women who undergo oocyte cryopreservation think about the process as a means to preserve fertility?

Hodes-Wertz B, Druckenmiller S, Smith M, Noyes N.Fertil Steril. 2013 Nov;100(5):1343-9. doi: 10.1016/j.fertnstert.2013.07.201. Epub 2013 Aug 13.PMID: 23953326 Free article.30CiteShare 

Increased risk of pregnancy-induced hypertension in young recipients of donated oocytes.

Keegan DA, Krey LC, Chang HC, Noyes N.Fertil Steril. 2007 Apr;87(4):776-81. doi: 10.1016/j.fertnstert.2006.08.105. Epub 2007 Jan 29.PMID: 17258714 Free article.31CiteShare 

Experiences in fertility preservation: lessons learned to ensure that fertility and reproductive autonomy remain options for cancer survivors.

Noyes N, Melzer K, Druckenmiller S, Fino ME, Smith M, Knopman JM.J Assist Reprod Genet. 2013 Oct;30(10):1263-70. doi: 10.1007/s10815-013-0066-2. Epub 2013 Aug 13.PMID: 23942892 Free PMC article.32CiteShare 

Programmatic implementation of blastocyst transfer in a university-based in vitro fertilization clinic: maximizing pregnancy rates and minimizing triplet rates.

Grifo JA, Flisser E, Adler A, McCaffrey C, Krey LC, Licciardi F, Noyes N, Kump LM, Berkeley AS.Fertil Steril. 2007 Aug;88(2):294-300. doi: 10.1016/j.fertnstert.2006.10.005. Epub 2007 May 25.PMID: 1753199533CiteShare 

Laboratory evaluation in oocyte cryopreservation suggests retrieved oocytes are comparable whether frozen for medical indications, deferred reproduction or oocyte donation.

Werner M, Reh A, Labella PA, Noyes N.J Assist Reprod Genet. 2010 Nov;27(11):613-7. doi: 10.1007/s10815-010-9455-y. Epub 2010 Jul 28.PMID: 20665237 Free PMC article.34CiteShare 

Evaluating the role of exogenous luteinizing hormone in poor responders undergoing in vitro fertilization with gonadotropin-releasing hormone antagonists.

Chung K, Krey L, Katz J, Noyes N.Fertil Steril. 2005 Aug;84(2):313-8. doi: 10.1016/j.fertnstert.2005.02.028.PMID: 16084870 Free article.35CiteShare 

Young Women’s Attitudes Towards Modern Reproductive Practices: A Survey Study Assessing What Young Women Want.

Druckenmiller S, DeVore S, Knopman JM, Noyes N.J Reprod Med. 2017 Mar-Apr;62(3-4):111-18.PMID: 3023030136CiteShare 

Retrospective analysis of outcomes following transfer of previously cryopreserved oocytes, pronuclear zygotes and supernumerary blastocysts.

Hodes-Wertz B, Noyes N, Mullin C, McCaffrey C, Grifo JA.Reprod Biomed Online. 2011 Jul;23(1):118-23. doi: 10.1016/j.rbmo.2011.03.020. Epub 2011 Mar 26.PMID: 2155030537CiteShare 

Oral contraceptive pretreatment in women undergoing controlled ovarian stimulation in ganirelix acetate cycles may, for a subset of patients, be associated with low serum luteinizing hormone levels, reduced ovarian response to gonadotropins, and early pregnancy loss.

Meldrum DR, Scott RT Jr, Levy MJ, Alper MM, Noyes N.Fertil Steril. 2009 May;91(5):1963-5. doi: 10.1016/j.fertnstert.2008.01.007. Epub 2008 Mar 12.PMID: 18339377 Free article.38CiteShare 

Low ectopic pregnancy rates after in vitro fertilization: do practice habits matter?

Keegan DA, Morelli SS, Noyes N, Flisser ED, Berkeley AS, Grifo JA.Fertil Steril. 2007 Sep;88(3):734-6. doi: 10.1016/j.fertnstert.2006.11.169. Epub 2007 Feb 20.PMID: 17316634 Free article.39CiteShare 

Live birth in a 46 year old using autologous oocytes cryopreserved for a duration of 3 years: a case report documenting fertility preservation at an advanced reproductive age.

Maxwell SM, Goldman KN, Labella PA, McCaffrey C, Noyes NL, Grifo J.J Assist Reprod Genet. 2014 Jun;31(6):651-5. doi: 10.1007/s10815-014-0202-7. Epub 2014 Mar 8.PMID: 24610096 Free PMC article. No abstract available.40CiteShare 

Impact of developmental stage at cryopreservation and transfer on clinical outcome of frozen embryo cycles.

Noyes N, Reh A, McCaffrey C, Tan O, Krey L.Reprod Biomed Online. 2009;19 Suppl 3:9-15. doi: 10.1016/s1472-6483(10)60279-9.PMID: 2003441941CiteShare 

Treatment outcomes and quality-of-life assessment in a university-based fertility preservation program: results of a registry of female cancer patients at 2 years.

Reh AE, Lu L, Weinerman R, Grifo J, Krey L, Noyes N.J Assist Reprod Genet. 2011 Jul;28(7):635-41. doi: 10.1007/s10815-011-9559-z. Epub 2011 Mar 22.PMID: 21424818 Free PMC article.42CiteShare 

Use of hormone suppression then oocyte freezing to preserve reproductive capability in an adolescent girl with ovarian luteinized thecoma associated with sclerosing peritonitis.

Noyes N, Perretta RC, Fino ME, Matulewicz T, Barakat R.Fertil Steril. 2009 Jul;92(1):393.e11-4. doi: 10.1016/j.fertnstert.2009.01.145. Epub 2009 Mar 26.PMID: 19327766 Free article.43CiteShare 

Delivery rate using cryopreserved oocytes is comparable to conventional in vitro fertilization using fresh oocytes: potential fertility preservation for female cancer patients.

Grifo JA, Noyes N.Fertil Steril. 2010 Feb;93(2):391-6. doi: 10.1016/j.fertnstert.2009.02.067. Epub 2009 May 12.PMID: 19439285 Free article.44CiteShare 

Cryopreserved oocytes can serve as the treatment for secondary infertility: a novel model for egg donation.

Knopman JM, Noyes N, Grifo JA.Fertil Steril. 2010 May 1;93(7):2413.e7-9. doi: 10.1016/j.fertnstert.2009.12.004. Epub 2010 Jan 25.PMID: 20097336 Free article.45CiteShare 

Heterotopic Gestation with Twin Intrauterine Implantation Following Transfer of Three Developmentally-delayed Embryos from Cryopreserved Oocytes: A Case Report.

Goldman KN, Keltz J, Berg RE, Noyes NL.J Reprod Med. 2015 Sep-Oct;60(9-10):436-40.PMID: 26592072